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Yasunari Sakai Selected Research

8-oxodeoxyguanosine triphosphate

9/2003An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress.
3/2002A molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1.

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Yasunari Sakai Research Topics

Disease

6Epilepsy (Aura)
11/2021 - 03/2016
5Seizures (Absence Seizure)
11/2021 - 04/2009
4Infections
01/2022 - 04/2009
3Mitochondrial Diseases (Mitochondrial Disease)
07/2022 - 09/2003
3Subacute Sclerosing Panencephalitis (SSPE)
01/2021 - 07/2005
3Autism Spectrum Disorder
01/2018 - 06/2011
2Pain (Aches)
11/2022 - 06/2021
2Tachycardia (Tachyarrhythmias)
11/2021 - 08/2017
2Leukemia
11/2021 - 09/2017
2Mucocutaneous Lymph Node Syndrome (Kawasaki Disease)
07/2021 - 01/2021
2Inflammation (Inflammations)
01/2021 - 03/2016
2Arteritis
01/2021 - 01/2014
2Paralysis (Palsy)
01/2020 - 11/2018
2Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
11/2019 - 07/2014
2Brain Diseases (Brain Disorder)
04/2019 - 01/2019
2Neoplasms (Cancer)
11/2018 - 09/2017
2Rett Syndrome (Rett's Disorder)
01/2018 - 09/2013
2Febrile Seizures (Febrile Seizure)
04/2009 - 08/2005
1Thiamine Deficiency
11/2022
1Beriberi
11/2022
1Avitaminosis (Vitamin Deficiency)
11/2022
1Heart Arrest (Cardiac Arrest)
11/2022
1Scurvy (Scorbutus)
11/2022
1Down Syndrome (Down's Syndrome)
07/2022
1Localized Scleroderma (Morphea)
01/2022
1Sepsis (Septicemia)
01/2022
1Myositis (Idiopathic Inflammatory Myopathies)
01/2022
1Hypertension (High Blood Pressure)
11/2021
1Persistent Infection
10/2021
1Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)
09/2021
1Metatropic dwarfism
07/2021
1Peripheral Nervous System Diseases (PNS Diseases)
07/2021
1Demyelinating Diseases (Demyelinating Disease)
06/2021
1Optic Neuritis (Retrobulbar Neuritis)
06/2021
1Cognitive Dysfunction
06/2021
1CDKL5 deficiency disorder
04/2021
1Ganglioglioma
01/2021
1Cerebellar Neoplasms
01/2021
1Chronic Obstructive Pulmonary Disease (COPD)
01/2021
1Vasculitis (Vasculitides)
01/2021
1Neurofibromatosis 1 (Neurofibromatosis Type I)
12/2020
1Neurodevelopmental Disorders
09/2020
1Cerebral Hemorrhage
04/2020
1Cough
02/2020
1Pneumonia (Pneumonitis)
02/2020
1Retinoblastoma (Glioblastoma, Retinal)
01/2020

Drug/Important Bio-Agent (IBA)

3Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2018
3Proteins (Proteins, Gene)FDA Link
09/2013 - 11/2008
2Anticonvulsants (Antiepileptic Drugs)IBA
11/2021 - 01/2020
2VaccinesIBA
07/2021 - 01/2019
2InterferonsIBA
01/2021 - 01/2020
2Phospholipids (Phosphatides)FDA LinkGeneric
01/2021 - 01/2021
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2020 - 01/2018
2CytokinesIBA
01/2020 - 04/2009
2Messenger RNA (mRNA)IBA
11/2019 - 07/2005
2Brain-Derived Neurotrophic Factor (BDNF)IBA
11/2019 - 10/2017
2Anti-Bacterial Agents (Antibiotics)IBA
05/2019 - 09/2017
2Biological ProductsIBA
01/2018 - 01/2016
2Methyl-CpG-Binding Protein 2IBA
01/2018 - 09/2013
2Pro-Opiomelanocortin (Proopiomelanocortin)IBA
10/2016 - 03/2016
28-oxodeoxyguanosine triphosphateIBA
09/2003 - 03/2002
1VitaminsIBA
11/2022
1Dopamine (Intropin)FDA LinkGeneric
07/2022
1Nuclear Receptor Interacting Protein 1IBA
07/2022
1Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaIBA
07/2022
1SteroidsIBA
01/2022
1Vitamin A (Retinol)FDA LinkGeneric
10/2021
1CationsIBA
07/2021
1CalciumIBA
07/2021
1Immunoglobulin G (IgG)IBA
06/2021
1Myelin-Oligodendrocyte GlycoproteinIBA
06/2021
1CyclinsIBA
04/2021
1alectinibIBA
01/2021
1Phosphatidylcholines (Phosphatidylcholine)IBA
01/2021
1LDL Lipoproteins (beta Lipoproteins)IBA
01/2021
1Ribavirin (Virazole)FDA LinkGeneric
01/2021
1Oxygen (Dioxygen)IBA
01/2021
1InflammasomesIBA
01/2021
1ColforsinIBA
12/2020
1DNA (Deoxyribonucleic Acid)IBA
09/2020
1carbazochrome (Adona)IBA
04/2020
1Indicators and Reagents (Reagents)IBA
02/2020
1Interleukin-6 (Interleukin 6)IBA
01/2020
1CarbohydratesIBA
01/2020
1Interleukin-2 Receptors (IL 2 Receptor)IBA
01/2020
1Calcium Channels (Calcium Channel)IBA
01/2020
1tulobuterolIBA
01/2020
1Glucose (Dextrose)FDA LinkGeneric
01/2020

Therapy/Procedure

5Drug Therapy (Chemotherapy)
11/2021 - 09/2017
3Critical Care (Surgical Intensive Care)
11/2022 - 04/2019
3Therapeutics
11/2021 - 09/2017
2Radiotherapy
01/2020 - 11/2018
1Intravenous Infusions
11/2022
1Enteral Nutrition (Feeding, Tube)
11/2022
1Length of Stay
01/2022
1Activities of Daily Living (ADL)
01/2022
1Transplantation
09/2021
1Intraventricular Infusions
01/2021
1Electrodes (Electrode)
01/2021
1Positive-Pressure Respiration (Positive End-Expiratory Pressure)
01/2020